Asymmetric palladium-catalyzed umpolung cyclization of allylic acetate-aldehyde using formate as a reductant.
نویسندگان
چکیده
Palladium/chiral diphosphine-catalyzed umpolung cyclization of allylic acetate-aldehyde using formate as a terminal reductant affords cis-disubstituted pyrrolidine, tetrahydrofuran, and spiro carbocycle in high enantioselectivity. The formate does not cause allylpalladium reduction under the catalysis. The highly stereoselective cyclization would proceed through a cationic η(1)-allylpalladium ligated by diphosphine.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 38 شماره
صفحات -
تاریخ انتشار 2015